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・ Dipeptidase M
・ Dipeptide
・ Dipeptide hydrolase
・ Dipeptidyl aminopeptidase III
・ Dipeptidyl carboxypeptidase
・ Dipeptidyl peptidase
・ Dipeptidyl peptidase-4
・ Dipeptidyl peptidase-4 inhibitor
・ Dioxathion
・ Dioxetane
・ Dioxetanedione
・ Dioxeuta
・ Dioxin
・ Dioxin Affair
・ Dioxin Reassessment Report
Dioxins and dioxin-like compounds
・ Dioxippe
・ Dioxippus
・ Dioxirane
・ Dioxolane
・ Dioxosuccinic acid
・ Dioxotetrahydropyrimidine phosphoribosyltransferase
・ Dioxybenzone
・ Dioxycanus
・ Dioxycanus fusca
・ Dioxycanus oreas
・ Dioxygen difluoride
・ Dioxygen in biological reactions
・ Dioxygenase
・ Dioxygenyl


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Dioxins and dioxin-like compounds : ウィキペディア英語版
Dioxins and dioxin-like compounds
Dioxins and dioxin-like compounds (DLCs) are by-products of various industrial processes, and are commonly regarded as highly toxic compounds that are environmental pollutants and persistent organic pollutants (POPs).〔(【引用サイトリンク】title=Are the dioxins the most dangerous chemicals in our environment? )〕 They include:〔(【引用サイトリンク】title=Synopsis on dioxins and PCBs )〕〔
* Polychlorinated dibenzo''-p-''dioxins (PCDDs), or simply dioxins. PCDDs are derivatives of dibenzo''-p-''dioxin. There are 75 PCDDs, and seven of them are specifically toxic.
* Polychlorinated dibenzofurans (PCDFs), or furans. PCDFs are derivatives of dibenzofuran. There are 135 congeners (derivatives differing only in the number and location of chlorine atoms). Whilst they strictly speaking are not dioxins, ten of them have "dioxin-like" properties.
* Polychlorinated biphenyls (PCBs), which also are not dioxins, but twelve of them have "dioxin-like" properties. Under certain conditions PCBs may form dibenzofurans through partial oxidation.
* Finally, dioxin may refer to dioxin proper, the basic chemical unit of the more complex dioxins. This simple compound is not persistent and has no PCDD-like toxicity.

PCDD general structure.png|Polychlorinated dibenzo''-p-''dioxins
PCDF general structure.svg|Polychlorinated dibenzofurans
PCB structure general.svg|Polychlorinated biphenyls
1,4-Dioxin.svg|1,4-dioxin

Because dioxins refer to such a broad class of compounds that vary widely in toxicity, the concept of toxic equivalence (TEQ) has been developed to facilitate risk assessment and regulatory control. Toxic equivalence factors (TEFs) exist for seven congeners of dioxins, ten furans and twelve PCBs. The reference congener is the most toxic dioxin 2,3,7,8-tetrachlorodibenzo-''p''-dioxin (TCDD) which per definition has a TEF of one.
In reference to their importance as environmental toxicants the term dioxins is used almost exclusively to refer to the sum of compounds (as TEQ) from the above groups which demonstrate the same specific toxic mode of action associated with TCDD. These include 17 PCDD/Fs and 12 PCBs. Incidents of contamination with PCBs are also often reported as dioxin contamination incidents since it is this toxic characteristic which is of most public and regulatory concern.
==Toxicity==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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